Developments in SPE techniques such as selective sorbents and in the overall approach to SPE, such as hybrid SPE and molecularly imprinted polymer SPE, have been addressed. The last decade has witnessed a rapid development of novel sample preparation techniques in bioanalysis. Conventional liquid–liquid extraction (LLE), protein precipitation (PP) and solid-phase extraction (SPE) techniques are now been considered as methods of the past. Multilingual: Translated into many languages.This paper reviews the recent developments in bioanalysis sample preparation techniques and gives an update on basic principles, theory, applications and possibilities for automation, and a comparative discussion on the advantages and limitation of each technique.Multi-platform: Runs on Windows, Mac, and some Linux distributions.No Ads: Enjoy an ad-free experience as you watch.Familiar design: YouTube-like design makes it easy to switch to FreeTube.Local data: All registrations and history are stored locally.Import subscriptions: Import your subscriptions from YouTube to see your feed instantly.Privacy: Your viewing habits are not tracked by us or YouTube.Sign up: Subscribe to channels without an account.The program allows you to subscribe to YouTube channels and like clips even without a Google account. It allows you to watch YouTube videos anonymously on your computer and download them as MP4 files if needed. With many similar features to YouTube, FreeTube has become one of the best methods to watch YouTube privately on desktop. FreeTube gets the data by removing the necessary information (either by local methods or by optionally using the Invidious API). All your user data is stored locally and is never sent or published to the internet. You can enjoy your favorite content and creators without your habits being tracked.

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